Primary Ovarian Non-Hodgkin's Lymphoma: A Rare Case Scenario

Abstract

One of the very rare types of the ovarian tumor is lymphoma. Lymphoma, presenting with ovarian mass as an initial manifestation, is a rare entity and may cause confusion for the clinician since its presentation might resemble with others, much more frequent primary ovarian tumors. To report an uncommon case of primary ovarian non-Hodgkin’s lymphoma in a peri-menarche girl with an attempt to delineate the clinical features and characteristics of this tumor with respect to histological findings. A 13-year of aged young girl was admitted with signs and symptoms suggestive of an ovarian tumor. Histopathology of the ovarian mass was done after an exploratory laparotomy. After surgery, Computed tomography (CT) of the chest, abdomen and pelvis, serum CA-125 and a bone marrow study were also done. Computed tomography revealed a heterogeneous mass, measuring 6.5×5.5 cm in diameter. Diagnosis of non-Hodgkin’s lymphoma was made on histopathology. Tumor was classified as a diffuse large B cell lymphoma. The patient was treated with surgery followed by chemotherapy using standard CHOP regimen using cyclophosphamide, doxorubicin, vincristine and prednisolone. She has now been without disease for 9 months after the surgery and chemotherapy. According to previous reports the treatment principles and prognosis of primary ovarian lymphoma is the same as that of other nodal lymphomas.