Hematological Parameters of Hypertensive and Normotensive Individuals in Rajshahi Medical College Hospital

Abstract

Background: Hypertension is a global health issue affecting cardiovascular function and associated with significant Hematological changes. Objective: This study compares Hematological parameters, such as MCV, MCH, MCHC, and hematocrit, between hypertensive and normotensive individuals at Rajshahi Medical College Hospital. Method: In a cross-sectional study of 240 participants (120 hypertensive, 120 normotensive), data were collected through structured interviews. Hematological parameters were analyzed to assess variations between groups. Result: Among hypertensives, 75.0% were male and 70.8% were married, while 33.3% were smokers, compared to 16.7% smokers in the non-hypertensive group. Income analysis showed that 56.7% of hypertensives earned less than 15,000 BDT monthly, compared to 58.3% of non-hypertensives. In terms of blood pressure, 98.3% of hypertensives had systolic BP >130 mmHg, and 95.8% had diastolic BP >90 mmHg, versus only 16.7% and 12.5% in the non-hypertensive group. Hematological findings revealed that 90.0% of hypertensives had hemoglobin >18 gm/dl, and 85.0% had hematocrit >50%. Additionally, 91.7% of hypertensives had an MCV <80 fL, whereas 90.0% of non-hypertensives had MCV within the 80-100 fL range. These results emphasize the substantial correlation between hypertension and certain socio-demographic and hematological factors, underscoring the importance of focused prevention efforts in high-risk populations. Conclusions: The study identifies significant Hematological differences in hypertensive patients, emphasizing the potential of these markers in risk assessment. Further investigation is recommended.